Pipeline

Pipeline

GBT is advancing a strategic drug discovery, development and commercialization approach that leverages the team’s expertise in blood biology and structural and medicinal chemistry.

GBT440 Program Overview

Sickle cell disease

HOPE Study
(all genotypes; chronic treatment of adults and adolescents)
    
HOPE-KIDS 1 Study
(safety, exploratory efficacy and PK in 12-17 year olds)
    

Hypoxemia Program

Idiopathic pulmonary fibrosis
(IPF; oxygen independent)
    
ZEPHYR
(IPF; oxygen dependent)
    
Basecamp
(healthy volunteers)